Delayed epithelial healing following photorefractive keratectomy with mitomycin C treatment

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Mitomycin C in photorefractive keratectomy.

PURPOSE To evaluate the outcome of primary or retreatment photorefractive keratectomy (PRK) or phototherapeutic keratectomy (PTK) with mitomycin C (MMC) 0.02% applied prophylactically intraoperatively for the prevention of haze and regression in cases of significant haze and regression after primary PRK, due to previous radial keratotomy (RK), in primary PRK eyes with high myopia, and in comeas...

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Outcomes of Photorefractive Keratectomy with Intraoperative Mitomycin-C

PURPOSE To report the efficacy, safety, predictability and complications of photorefractive keratectomy (PRK) with intraoperative application of mitomycin-C (MMC). METHODS This historical cohort study was performed on 1,250 eyes of 625 patients who underwent PRK using the Technolas 217 excimer laser machine by a single surgeon with intraoperative use of MMC 0.02% up to 2 minutes, depending on...

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Corneal epithelial recovery following photorefractive keratectomy.

AIMS To further understand the morphological and functional recovery of corneal epithelium following excimer laser photorefractive keratectomy (PRK). METHODS The right eyes (group 1) of 15 male, New Zealand white rabbits weighing 2-3 kg underwent PRK. The left eye of each rabbit (group 2) underwent simple mechanical de-epithelialisation and were examined as treated controls. Both eyes of anot...

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Effect of Mitomycin C on Myopic versus Astigmatic Photorefractive Keratectomy

Purpose. Long-term mitomycin C (MMC) effects on photorefractive keratectomy (PRK) were compared in simple myopic and astigmatic patients. Methods. In this observational cohort study, subjects were selected based on preoperative and postoperative data collected from medical records; they were divided into simple myopia with/without MMC and myopic astigmatism with/without MMC groups. Haze, uncorr...

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Corneal epithelial healing after photorefractive keratectomy: analytical study.

PURPOSE To characterize the velocity of epithelial migration after photorefractive keratectomy (PRK) with 3 different corneal ablation patterns. SETTING Department of Ophthalmology, Catholic University of Rome, Rome, Italy. METHODS Fifteen patients (30 eyes) with mild to moderate myopia and with simple to compound myopic astigmatism were enrolled for this study. The surgical procedure consi...

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ژورنال

عنوان ژورنال: Acta Ophthalmologica

سال: 2010

ISSN: 1755-375X

DOI: 10.1111/j.1755-3768.2010.01894.x